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Sleepdex - Resources for Better Sleep

Familial Advanced Sleep-Phase Syndrome

Have you ever asked yourself, “Why am I yawning when it’s only 6:30 in the evening?” Or, do you ever ask yourself, “Why do I get so tired so early and get up so early? Can’t I be normal like everyone else?” Well, the cause and solution may be more than just being too tired too early. You and millions of people the world over may be suffering bouts of Familial Advanced Sleep-Phase Syndrome. This aforesaid syndrome could be exactly what’s robbing you of a quality night’s sleep.

Sufferers of Familial Advanced Sleep-Phase Syndrome invariably go to bed and rise early, conventionally three to four hours earlier than the so-called normal sleeper. The circadian rhythm—our body’s processes recurring naturally on a twenty-four hour cycle—of such people is biologically different. The disorder causes melatonin blood levels and the core temperature of the body to cycle at earlier times than others. Geneticists suggest that the inherent problem could be near the 2q gene, or in the hPer2 gene, controlled by the prachiasmatic nucleus of the hypothalamus. Mutations of the gene cause a serine to glycine mutation. Essentially, the body’s natural schedule becomes corrupted where the gene is missing a necessary component and altering typical circadian rhythm.

People with Familial Advanced Sleep-Phase Syndrome conventionally show a near normal sleep pattern of normal quality and span; however, the sleep onset occurs earlier than desired. Other symptoms occurring for more than three months at a time include the inability to stay away until “normal” bedtime or where the opposite is true, and sufferers have the inability to remain asleep until “normal” wake time. Symptoms of this degree usually occur in the elderly more than in their younger counterparts.

Moreover, the affected have less daytime or afternoon energy and alertness, may overdose on sleep medications or alcohol and suffer emotional and physical problems. Statistics show that those with Familial Advanced Sleep-Phase Syndrome are evenly distributed between men and women, and as high as one-third of the population in the US may show signs of the disorder. Additionally, the condition might bring about digestive complications: diarrhea, cramping, abdominal pains, ulcers and constipation.

Treatment for Familial Advanced Sleep-Phase Syndrome involves chronotherapy, which take into account the body’s natural rhythms, along with bright light therapy. The latter attempts to cause the body to think it is daylight longer due to extended light exposure. Such apparatuses are generally installed in the house to slow down the sleep phase. Some success has been found in acupuncture. On the other hand, melatonin treatments have had little success, with side affects including nightmares, sleeplessness, accompanied by uncontrollable yawning. Often, when treatment is not successful, those afflicted with Familial Advanced Sleep-Phase Syndrome must adapt their social and physical lifestyles to fit the phases of the disturbance.


 

 

 

 

 

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"It’s been a hard day’s night
I’ve been workin´ like a dog
It’s been a hard day’s night
And I’ll be sleepin´ like a log…. "

(John Lennon and Paul McCartney)

 

 

Statue of a sleeping soldier